Overview
The Stanford Alzheimer’s Disease Research Center (ADRC) is part of the U.S. NIA-funded Alzheimer’s Disease Centers Program, dedicated to advancing research on Alzheimer’s disease and related dementias. The center integrates clinical, cognitive, neuroimaging, genetic, and biomarker data to study the progression, risk factors, and potential interventions for Alzheimer’s and related disorders.
Official Website: med.stanford.edu/adrc
Data Available in Mind Data Hub
Processing Status: Data ingestion completed — preprocessing is currently in progress. Once completed, available modalities will include:
Structural MRI (T1-weighted & T2-weighted)
Preprocessing Steps:
- Conversion to NIfTI format (If needed)
- Brain Extraction
- Registration to MNI Space using ANTs (Rigid + Affine transformations)
- Quality Control (QC)
Download Data Date: Aug 2025
Functional MRI (Resting-state fMRI)
- Conversion to NIfTI (BIDS format)
- Slice-timing and motion correction
- Brain extraction and normalization to MNI
- Denoising and smoothing
- Quality Control (QC) and time-series extraction
Download Data Date: Aug 2025.
Diffusion Tensor Imaging (DTI)
Preprocessing Steps:
- Convert DICOM to NIfTI
- Topup Correction (Using a top-up tool from FSL)
- Eddy Correction (Using eddy tool from FSL)
- Brain Extraction (Using Bet tool from FSL)
- Merging of Acquisitions (If the session is split into multiple scans)
- DTI Model Fitting(Using the Dtifit tool from FSL)
- Registration to MNI Space using ANTs (Rigid + Affine transformations)
- QC
Download Data Date: Aug 2025
Request Access to ADRC Data
To request access to ADRC data, please fill out our internal request form. Requests will be reviewed by our data management team.
Citation and Acknowledgment
When using ADRC data, please cite the official ADRC project and acknowledge the Mind Data Hub preprocessing pipeline:
"Data used in the preparation of this article were obtained from the Stanford Alzheimer’s Disease Research Center (ADRC) database (med.stanford.edu/adrc.html). The preprocessing and harmonization of data were performed by Mind Data Hub at Stanford University."
Useful Links